The anatomical problem posed by brain complexity and size: a potential solution

نویسنده

  • Javier DeFelipe
چکیده

Over the years the field of neuroanatomy has evolved considerably but unraveling the extraordinary structural and functional complexity of the brain seems to be an unattainable goal, partly due to the fact that it is only possible to obtain an imprecise connection matrix of the brain. The reasons why reaching such a goal appears almost impossible to date is discussed here, together with suggestions of how we could overcome this anatomical problem by establishing new methodologies to study the brain and by promoting interdisciplinary collaboration. Generating a realistic computational model seems to be the solution rather than attempting to fully reconstruct the whole brain or a particular brain region.

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Comments and General Discussion on “The Anatomical Problem Posed by Brain Complexity and Size: A Potential Solution”

Citation: DeFelipe J, Douglas RJ, Hill SL, Lein ES, Martin KAC, Rockland KS, Segev I, Shepherd GM and Tamás G (2016) Comments and General Discussion on “The Anatomical Problem Posed by Brain Complexity and Size: A Potential Solution”. Front. Neuroanat. 10:60. doi: 10.3389/fnana.2016.00060 Comments and General Discussion on “The Anatomical Problem Posed by Brain Complexity and Size: A Potential ...

متن کامل

Numerical Solution of a Free Boundary Problem from Heat Transfer by the Second Kind Chebyshev Wavelets

In this paper we reduce a free boundary problem from heat transfer to a weakly Singular Volterra  integral equation of the first kind. Since the first kind integral equation is ill posed, and an appropriate method for such ill posed problems is based on wavelets, then we apply the Chebyshev wavelets to solve the integral equation. Numerical implementation of the method is illustrated by two ben...

متن کامل

A New Approach for Solving Heat and Mass Transfer Equations of Viscoelastic Nanofluids using Artificial Optimization Method

The behavior of many types of fluids can be simulated using differential equations. There are many approaches to solve differential equations, including analytical and numerical methods. However, solving an ill-posed high-order differential equation is still a major challenge. Generally, the governing differential equations of a viscoelastic nanofluid are ill-posed; hence, their solution is a c...

متن کامل

AN ADAPTIVE WAVELET SOLUTION TO GENERALIZED STOKES PROBLEM

In this paper we will present an adaptive wavelet scheme to solvethe generalized Stokes problem. Using divergence free wavelets, theproblem is transformed into an equivalent matrix vector system, thatleads to a positive definite system of reduced size for thevelocity. This system is solved iteratively, where the applicationof the infinite stiffness matrix, that is sufficiently compressible,is r...

متن کامل

Non-linear stochastic inversion of regional Bouguer anomalies by means of Particle Swarm Optimization: Application to the Zagros Mountains

Estimating the lateral depth variations of the Earth’s crust from gravity data is a non-linear ill-posed problem. The ill-posedness of the problem is due to the presence of noise in the data, and also the non-uniqueness of the problem. Particle Swarm Optimization (PSO) is a stochastic population-based optimizer, originally inspired by the social behavior of fish schools and bird flocks. PSO is ...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:

دوره 9  شماره 

صفحات  -

تاریخ انتشار 2015